Motor Ocular Neuropathy Caused by Mefloquine

Mefloquine is widely used for prophylaxis and treatment of malaria. It can induce a range of neurological side effects and its’ neurotoxic potential with neuron apoptosis and significant axonal degeneration was confirmed in several in vitro studies. We report a patient presented with rare symptoms of relapsing motor neuropathy involving extraocular muscles, primary m. levator palpebrae, occuring while the mefloquine treatment.