Applying Laser Doppler Technology To Measure The Function Of The Microcirculation

Applying Laser Doppler Technology to Measure theFunction of the MicrocirculationXu Shunchao, Xia Luoling, Song Peiying,Wang Junpei, Shi Xiafeng, Li YuenanShanghai Institute of Laser Technology319 Yue Yang Road, 200031, Shanghai, China1. IntroductionAn erfective and noninvasive new arrangement to measure the function of microcirculationblood flow is presented in this paper. This set -up has been used in many hospitals and medicalinstitutes to observe how the microcirculation blood flow of men or animals is affected by med-icaments and pathology phenomenon etc.. Major merits of the set -up are that it can continuous-ly measure both blood flow velocities and diameter for a single vasa. Using the arrangement,we can obtain the average value of blood flow velocities and pulsation wave of blood flow. Wecan also record variation curves of the microvasa diameter and the blood flow velocities overa long period with a multichannel voltage recorder. The experimental results show that thisset -up will make notable impact on the biomedicine research with its definite clinical appli-cation value.2. Experimental ArrangementAccording to Laser Doppler effect, frequency changes of scattering light from motional redblood cells can occur, the Doppler shifts are proportinal to blood flow velocities. The ex-perimental set -up is illustrated in Fig.1. The new set -up consists of a back Laser Dopplermicroscope and a TV- microscope system. A laser beamfrom the Re -Ne laser (1) is split into two beams