Immune Effects of Polysaccharide from Portulaca oleracea on Mice With Tumor S_(180)

In order to evaluate the effects of Portulaca oleracea polysaccharide (POP) on immune effects in Sarcoma_180,the POP was obtained by water extraction and alcohol precipitation from Portulaca oleracea and was administered on the Sarcoma_180with 50 mg/kg、100 mg/kg and 200 mg/kg respectively by intraperitoneal injection(IP) for 10 d. The inhibition rate of tumor growth、lymphocyte Proliferation phagocytic activity and IL-1 IL-2 were investigated. The POP could significantly inhibit tumor growth;the inhibition rates of tumor growth were 16.92,51.45 and 64.96 (%). Compared with NS group ,the POP increased lymphocyte transformation capacity Phagocytic activity and the IL-1 and IL-2. secretion. The POP has obvious antineoplastic effect,and the main mechanism is to enhance the immune function of Sarcoma_180.