Disposition and elimination of minor tranquilizers in the aged and in patients with liver disease.
1978
ABSTRACTBoth old age and liver disease may affect the disposition and elimination of drugs and in the case of sedatives and tranquilizers such abnormalities may be associated with exaggerated sedation. Diazepam (Valium) elimination half-life (T) increases with advancing age and it correlates with in
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