Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia

Tuberculosis (TB) remains major Public health problem and among the top ten leading causes of human deaths worldwide. Moreover, TB is the leading cause of morbidity, one of the three major causes for hospital admission, and the second killer next to malaria in Ethiopia. Early diagnosis, effective treatment and continues assessment of treatment outcome are important to improve TB management program. Retrospective study design was conducted to assess trend and treatment outcomes of TB in Debre Berhan referral hospital. 4 years (2014 to 2017) TB case records was reviewed with standard check list and entered in to EpiData 3.1 and analyzed using SPSS version 16. Among the total registered TB patients with complete record (n=506), 256(50.6%) were males and 250(49.4%) Female. The treatment cured rate varies from 23.29% in 2006 E.C to 47.45% in 2007 E.C, whereas treatment completed varies from 46.91% in 2007 E.C to 67.08% in 2009 E.C. Majority of the smear-positive pulmonary tuberculosis patients 183 (97.3%) were cured at the end of their anti-TB treatment. The proportion of HIV co-infection among TB patients was 21.3%. However, overall cure rate was nearly the same in both HIV positive and negative patients. As conclusion majority of the smear-positive pulmonary tuberculosis patients were cured at the end of their anti-TB treatment. There was also a continuous increment of treatment success rate, indicating that the hospital is within the track of WHO target currently. However the proportion of HIV co-infection among TB patients was higher which signifies the urgent need for staff capacity building and increasing public awareness.