A Comparative Study on Singhnad guggulu & Trayodasanga guggulu in the Management of Juvenile Rheumatoid Arthritis W.S.R to Amavata

Objective: The aim of present study was to compare the effect of Singhnad guggulu and Trayodasanga guggulu in the management of Juvenile rheumatoid arthritis w.s.r. to Amavata. Methods: 20 patients satisfying criteria of Juvenile rheumatoid arthritis of 7 to 16 yrs age group of either sex had been randomly selected from OPD & IPD of Hospital of University College of Ayurved, Dr. S.R. Rajasthan Ayurved University, Jodhpur, Rajasthan, India. They were divided into two groups of 10 each. Group A:  10 patients of this group were treated with Singhnad guggulu. Group B:  10 patients of this group were treated with Trayodasanga Guggulu . Both medicines were administered in a dose of 2mg/kg body weight /day (dose calculated by clark’s rule) for 45 days with luke warm water. Results: Singhnad guggulu in Group A was found to have statistically highly significant effect (<0.001) in controlling joint pain while significant effect (<0.05) was found  on all other three symptoms  joint swelling , joint stiffness and joint tenderness in juvenile rheumatoid arthritis affected patient as compared to Trayodasanga Guggulu .