Preparation method for 9-beta-D-arabinofuranosyl-2-fluoroadenine-5'-phosphate

2013 
The invention discloses a preparation method for 9-beta-D-arabinofuranosyl-2-fluoroadenine-5'-phosphate. The method employs 9-beta-D-arabinofuranosyl-2-fluoroadenine as an initial raw material, enables the raw material to be reacted with a mixture of triethyl phosphate and phosphorus oxychloride and employs water for post-processing, thereby solving the problems in other synthetic methods that reaction temperature is sever, reaction time is long and post-processing operation is complex. Also, the invention discloses a simple practicable refining method, and helps to effectively improve the purity of 9-beta-D-arabinofuranosyl-2-fluoroadenine-5'-phosphate.
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