Solution Phase Library of Perhydrooxazin-4-ones.

Abstract A general approach to the solution phase parallel synthesis of perhydrooxazin-4-ones, which allows the preparation of milligram quantities of each individual member, is reported. An efficient purification method, using as “Sequestration Enabling Reagent” (SER) aminomethylpolystyrene resin in the presence of trimethylorthoformate is also described.