Study on the anticomplement constituents from FLOS ROSAE RUGOSAE.

[Objective] To isolate and identify the anticomplement constituents from FLOS ROSAE RUGOSAE,the flower buds of Rosa rugosa Thunb.[Method] Diverse chromatographic methods were adopted to isolate and purify the anticomplement constituents,and then chemical structures of the compounds were compared and identified by using nuclear magnetic resonance,mass spectrum data and literature data.[Result] 3 flavonoids were isolated from the main active part of FLOS ROSAE RUGOSAE,including luteolin(1),quercetin(2) and kaempferol(3).[Conclusion] The FLOS ROSAE RUGOSAE extracts had in vitro anticomplement effect due to the flavonoids in the extracts.