MP18-09 ROLE FOR THE ECTONUCLEOTIDASE CD39: OUTCOME AND ASSOCIATION WITH PD-1/PD-L1 BASED CANCER IMMUNITY IN CLEAR CELL RENAL CELL CARCINOMA

INTRODUCTION AND OBJECTIVE:Extracellular adenosine generates a highly immunosuppressive microenvironment in solid tumors. The ectonucleotidases, CD39 and CD73, are important factors in adenosine pr...