Population Pharmacokinetic/Pharmacodynamic Modeling of Sunitinib by Dosing Schedule in Patients with Advanced Renal Cell Carcinoma or Gastrointestinal Stromal Tumor

Reza Khosravan,Robert J. Motzer,Elena Fumagalli,Brian I. Rini

Population Pharmacokinetic/Pharmacodynamic Modeling of Sunitinib by Dosing Schedule in Patients with Advanced Renal Cell Carcinoma or Gastrointestinal Stromal Tumor

2016

Reza Khosravan
Robert J. Motzer
Elena Fumagalli
Brian I. Rini

Background Sunitinib is a multi-targeted tyrosine kinase inhibitor used in the treatment of advanced renal cell carcinoma (RCC) and imatinib-resistant/intolerant gastrointestinal stromal tumors (GIST).

Keywords:

GiST
Stromal cell
Dosing
Renal cell carcinoma
Stromal tumor
Pharmacology
Tyrosine-kinase inhibitor
Oncology
Sunitinib
Population
Internal medicine
Medicine

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