Phenylethyl Glycosides from Digitalis lanata

Three new phenylethyl glycosides, 3′′′′-O-methylmaxoside (=2-(3,4-dihydroxyphenyl)ethyl O-β-D-glucopyranosyl-(13)-O-[β-D-glucopyranosyl-(16)]-4-O-(E)-feruloyl-β-D-glucopyranoside; 1), digilanatosides A (=2-(3,4-dihydroxyphenyl)ethyl O-6-O-(E)-sinapoyl-β-D-glucopyranosyl-(13)-4-O-(E)-caffeoyl-β-D-glucopyranoside; 2), and digilanatoside B (=2-(3,4-dihydroxyphenyl)ethyl O-6-O-(E)-p-coumaroyl-β-D-glucopyranosyl-(13)-4-O-(E)-caffeoyl-β-D-glucopyranoside; 3) were isolated from the aerial parts of Digitalis lanata, along with two known phenylethyl glycosides, purpureaside A and maxoside, a phenylpropanoid glucose ester, 1-O-(E)-feruloyl-β-glucopyranose, a benzoquinolethanoid glucoside, cornoside, a cardenolide, lanatoside C, a furostane-type steroidal saponin, purpureagitoside, and a disaccharide, sucrose. Their structures were elucidated on the basis of spectroscopic evidence (1D- and 2D-NMR, and HR-MALDI-MS).