GW24-e2132 Association between PM10 and emergency hospital visits for stroke in Changsha a case-crossover study

Objectives To investigate the relation between particulate matter with an aerodynamic diameter of 10 ) and emergency hospital visits (EHVs) for stroke in Changsha, China. Methods The daily EHVs for cerebral haemorrhage and cerebral infarction were gathered from the third Xiangya hospital during 2008-2009. The corresponding air pollutions and meteorological data were collected from the environmental protection agency and the weather bureau. The seasonal-stratified case-crossover design with 1:1 matched pair was used to set up single-pollution models and multi-pollution models for the data analysis. Results Adjusting the temperature and relative humidity in single-pollution models, an 10 μg/m 3 increase in PM 10 were significantly association with EHVs of cerebral haemorrhage and cerebral infarction at lags of 0 day [OR = 0.953 (95%CI: 0.871-1.042) and OR = 0.970 (95%:0.910-1.034), respectively], 1day [OR = 0.984 (95%CI: 0.913-1.061) and OR = 0.965 (95%: 0.902-1.031), respectively] and 2 day [OR = 0.996 (95%CI: 0.928-1.069) and OR = 0.964 (95%: 0.904-1.029), respectively] in autumn. But there was no significantly association between PM 10 and EHVs for cerebral haemorrhage and cerebral infarction in any other season. Conclusions The concentration of PM 10 was associated with increased EHVs for cerebral hemorrhage and cerebral infarction in Changsha.