Device and method for the enrichment and detection of cells in flowing media

2009 
Apparatus for the enrichment and continuous detection / acquisition of cells with • a channel (4) • a magnet (7) and • at least one magnetoresistor (3), wherein • the magnetoresistance (3) to the duct wall arranged • the channel configured to a laminar flow (5) of a medium having magnetically-labeled cells (1) on the magneto-resistance (3) to carry over, wherein • the device comprises a control device for controlling the flow velocity of the medium, and • the magnet is arranged so the outside in the region of the channel that • the magnetoresistance (3) between the channel inner wall and the magnet (7) and • the origin of the magnetic field lines of the magnet (7) the magnetic field generated is the magnetoresistance, so that • the magnetically labeled cells (1) from the laminar flow to the magnetoresistor (3) are introduced, and • the channel inner wall has a surface functionality, said surface functionalization is configured so that the cells are put on contact with the duct inner wall in rotation so that • The cells on the inner channel wall and thus roll • is a single-cell version guaranteed.
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