Superfund Innovative Technology Evaluation Program demonstration plan for Westinghouse Bio-Analytic Systems pentachlorophenol immunoassays

The plan provides a detailed design and description of the demonstration and evaluation program for the Westinghouse Bio-Analytic Systems immunoassay technologies specific for the analysis of pentachlorophenol. The immunoassays measure parts per billion concentrations of pentachlorophenol in water. The demonstration is being conducted under the Superfund Innovative Technology Evaluation (SITE) Program. It is expected that proper execution of the demonstration plan will provide information that enables data users and reviewers to assess the performance of the technology in terms of its usefulness and limitations for the Superfund Program. The main focus of the demonstration is to evaluate on site a semiquantitative immunoassay field analysis kit for its utility as a rapid field screening tool. The results obtained from the field kit analyses will be compared to those obtained from a quantitative high-sample-capacity plate immunoassay also developed by Westinghouse Bio-Analytic Systems. In addition, both immunoassay techniques will be compared to the standard gas chromatography/mass spectrometry procedure for pentachlorophenol determination. The quality assurance plan for the demonstration is provided in an appendix.