Intensified insulin treatment is associated with improvement in skin microcirculation and ischaemic foot ulcer in patients with type 1 diabetes mellitus: a long-term follow-up study

Aims/hypothesis We investigated skin microcirculation and its association with HbA1c and the incidence of ischaemic foot ulcer in patients with type 1 diabetes formerly randomised (1982–1984) to intensified conventional treatment (ICT) or standard treatment (ST) with insulin for a mean of 7.5 years.