Geographical pattern of chronic liver diseases in Italy: Results from two pooled national surveys

Abstract Background The information on the geographical characteristics of chronic liver diseases (CLD) in Italy is out-dated. Aim To provide up-dated information on the geographical pattern of patients with CLD born in Italy. Methods Patients with CLD were enrolled in two national surveys performed in 2001 and 2014, which prospectively recruited subjects aged ≥18 years referring to Italian liver units located throughout the country that apply a similar clinical approach and analytical methods. Results The total number of patients enrolled was 11,676. Alcohol-related CLD was more frequently observed in northern/central areas (25.0% vs. 20.7%, p  Conclusions These up-dated findings show different geographical patterns of CLD in Italy, reflecting different behavioural habits and socio-economic conditions across the country. They may be useful to apply more adequate preventive measures and to allocate economic resources.