Delivery of pDNA to lung epithelial cells using PLGA nanoparticles formulated with a cell-penetrating peptide: understanding the intracellular fate

Larissa Gomes dos Reis,Wing-Hin Lee,Maree Svolos,Lyn M. Moir,Rima Jaber,Andrea Engel,Norbert Windhab,Paul M. Young,Daniela Traini

Delivery of pDNA to lung epithelial cells using PLGA nanoparticles formulated with a cell-penetrating peptide: understanding the intracellular fate

2020

Larissa Gomes dos Reis
Wing-Hin Lee
Maree Svolos
Lyn M. Moir
Rima Jaber
Andrea Engel
Norbert Windhab
Paul M. Young
Daniela Traini

AbstractThe combination of nanoparticles (NPs) and cell-penetrating peptide (CPP) represents a new opportunity to develop plasmid DNA (pDNA) delivery systems with desirable properties for lung deli...

Keywords:

Endocytic cycle
Nanoparticle
PLGA
Cell biology
Chemistry
intracellular fate
Gene delivery
Chromatography
Lung
Cell-penetrating peptide
Peptide
plga nanoparticles

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