Comparative effectiveness and safety of oral anticoagulants in treatment of acute thromboses of deep veins of the lower extremities

: An analysis of complex examination and treatment of 101 patients with venous thromboembolism was made. The patients were divided into 3 groups. The first group consisted of 46 patients who had starting therapy during 7 days with heparin followed by taking phenylene during 6 months. The second group included 30 patients who were given warfarin instead of phenylene, 25 patients of the third group were treated with dabigatran. In the first group there were 21.7% of relapses, in the second group there were no relapses. In the third group there was 1 (4%) patient with a relapse of the disease due to congenital thrombophilia. Complications of anticoagulation therapy were noted in 23.9% of the first group patients, 20%--in the second group, and 16% of the third group patients.