Relationship between body fat composition and the severity of coronary artery disease

Objective:To explore the relationship between body fat distribution and the severity of coronary artery disease and compare the various methods of evaluating body fat distribution.Method:Sixty-nine coronary heart disease patients were enrolled.Epicardial fat volume(EFV),abdominal visceral fat volume(VFV),total fat volume(TFV)and subcutaneous fat volume(SFV)were measured by MSCT.Body length and body weight were measured,and to compute body mass index(BMI).Waist circumference(WC)and hip circumference(HC)were measured,and to compute waist to hip ratio(WHR).The severity of coronary artery disease was assessed by evaluating the extension of coronary plaques and the percentage coronary diameter stenosis.Analyze the relationship between body fat distribution and the severity of coronary artery disease,EFV and other indexes.Result:A positive correlation was shown between body weight,BMI,WC,WHR,VFV,TFV,EFV and the severity of coronary artery disease(P0.05).The relationship of VFV and EFV with the severity of coronary artery disease is the closest(r=0.356).A positive correlation was shown between body weight,BMI,WC,HC,WHR,VFV,TFV and EFV(P0.05).The relationship of EFV and VFV is the closest(r=0.630).Conclusion:VFV and EFV have a better relationship and could be a marker to reflect the severity of coronary artery disease.Visceral fat could be assessed by evaluating Epicardial fat.