Malignant melanoma arising in the skin lesions of Nagashima-type palmoplantar keratosis

Nagashima-type palmoplantar keratosis (PPK) is characterized by transgressive and non-progressive PPK with an autosomal recessive trait. Nagashima-type PPK was first described in a report from Japan in 1977 [1]. Although more than 20 cases of Nagashima-type PPK have been reported since then [2], no studies have been conducted in regard to the complications of this disorder. In this report, we present a case of malignant melanoma (MM) arising in the skin lesions of Nagashima-type PPK.A 64-year-old [...]