Evaluarea in vitro a alergiei mediate IgE la lichid seminal uman

Human seminal plasma allergy is a rare clinical entity with symptoms varying from local reactions to life-threatening anaphylaxis after unprotected sexual intercourse. It can be associated with localized urticaria to skin contact and can be more severe as a result of condomless receptive anal sex. The in vitro investigation of specific serum IgE against human seminal fluid and molecular canine allergen Can f 5, cross-reactive with human prostate specific antigen (PSA), may be performed in clinical practice by solid-phase immunoassay methods such as singleplex fluoroimmunoassay and a new generation multiplex macroarray nanotechnology-based immunoassay.