Trends in the Surgical Management of Crohn' sD isease

Introduction Although medical management of Crohn’s disease has changed in recent years, it is unclear whether surgical management has altered. We examined rate changes of surgical interventions, stoma constructions, and subset of ileostomy and colostomy constructions. Materials and Methods We reviewedthe NationwideInpatient Sampledatabasefrom1988to2011.We examinedthe number of Crohn’s-related operations and stoma constructions, including ileostomies and colostomies; a multivariable logistic regression model was developed. Results A total of 355,239 Crohn’s-related operations were analyzed. Operations increased from 13,955 in 1988 to 17,577 in 2011, p<0.001. Stoma construction increased from 2493 to 4283, p<0.001. The subset of ileostomies increased from 1201 to 3169, p<0.001 while colostomies decreased from 1351 to 1201, p=0.05. Operation percentages resulting in stoma construction increased from 18 to 24 %, p<0.001. Weight loss (OR 2.25, 95 % CI 1.88, 2.69) and presence of perianal fistulizing disease (OR 2.91, 95 % CI 2.31, 3.67) were most predictive for requiring stoma construction. Conclusions Crohn’s-related surgical interventions and stoma constructions have increased. The largest predictors for stoma construction are weight loss and perianal fistulizing disease. As a result, nutrition should be optimized and the early involvement of a multidisciplinary team should be considered.