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Structure-based de novo design and discovery of nonpeptide antagonists of the pp60src (Src) SH2 domain
Structure-based de novo design and discovery of nonpeptide antagonists of the pp60src (Src) SH2 domain
2002
Kimberly S. Para
Elizabeth A. Lunney
Mark S. Plummer
Charles J. Stankovic
Aurash Shahripour
Debra R. Holland
John R. Rubin
Humblet
James H. Fergus
James S. Marks
Susan Hubbell
Roman Herrera
Alan R. Saltiel
Tomi K. Sawyer
Keywords:
Lead compound
Combinatorial chemistry
Proto-oncogene tyrosine-protein kinase Src
SH2 domain
Chemistry
structure based
Computational biology
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