Biocompatible Nanoparticulate Systems for Tumor Diagnosis and Therapy

The sections in this article are Introduction Nanoscale Particulate Systems and their Building Blocks/Components Dendrimers Buckyballs and Buckytubes Quantum Dots Polymeric Micelles Liposomes Biodegradable Nanoparticles Preparation of Nanoparticles Biodegradable Optical Nanoparticles Optical Nanoparticles as a Potential Technology for Tumor Diagnosis Optical Nanoparticles as a Potential Technology for Tumor Treatment Optical Imaging and PDT Optical Imaging Fluorescence-based Optical Imaging NIR Fluorescence Imaging NIR Dyes for Fluorescence Imaging PDT Basis of PDT Photosensitizers for PDT ICG: An Ideal Photoactive Agent for Tumor Diagnosis and Treatment Clinical Uses of ICG Structure and Physicochemical Properties of ICG Binding Properties of ICG Metabolism, Excretion and Pharmacokinetics of ICG Toxicity of ICG Tumor Imaging with ICG PDT with ICG Limitations of ICG for Tumor Diagnosis and Treatment Recent Approaches for Improving the Blood Circulation Time and Uptake of ICG by Tumors Recent Approaches for ICG Stabilization In Vitro PLGA-based Nanoparticulate Delivery System for ICG Rationale of Using a PLGA-based Nanoparticulate Delivery System for ICG In Vivo Pharmacokinetics of ICG Solutions and Nanoparticles Conclusions and Future Work