Flavonoids and other constituents of Hymenostegia afzelii (Caesalpiniaceae)
2011
Abstract Phytochemical investigation of the stem bark and leaves of Hymenostegia afzelii resulted in the isolation of three new flavonoids, named afzelin A-C ( 1–3 ), together with five known compounds: 7,6-(2″,2″-dimethylpyrano)-3,5,4′-trihydroxyflavone, apigenin, 3- O -α- l -rhamnopyranosylcincholic acid, 3- O -β- d -glucopyranosylcincholic acid, and dodecanoic acid 1,1′-[(1 S )-1-(hydroxymethyl)-1,2-ethanediyl] ester. The structures of 1–3 were determined by means of spectroscopic methods. Compounds 1–3 were tested in vitro for their preliminary cytotoxicity using the Artemia salina assay.
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