Optimization of KOH-catalyzed methanolysis of hempseed oil

Abstract The methanolysis of hempseed oil catalyzed by potassium hydroxide was studied using the full central composite rotatable design. The methanolysis reaction was modeled and optimized by the response surface methodology (RSM) and an artificial neural network model combined with a genetic algorithm (ANN-GA). All individual factors have significant influence on the FAME content ( p -value