Hyperthyroidism associated with adenomatous goiter in an infant

We operated on a 5-year-old girl with adenomatous goiter and hyperthyroidism. Since the age of 6 months, the patient had had delayed growth and a large goiter; the serum level of thyroid iodine was high, and the diagnosis of hyperthyroidism was made. Treatment with propylthiouracil (PTU) was started. Circulating thyrotropin receptor antibody and long-acting thyroid stimulator were not detected. The patient continued to require PTU to remain euthyroid. When she was 5, the goiter was enlarged, and subtotal thyroidectomy was done. The diagnosis of adenomatous goiter was made. The postoperative course was uneventful. Two years after the operation, the patient remains euthyroid without medication.