Analysis Procedure protein disulfide isomerase for the in vitro diagnosis of colorectal cancer

In vitro assay for colorectal cancer diagnosis by determining the presence of marker protein disulfide isomerase (PDI) in a biological sample from a patient suspected to be affected by colorectal cancer using at least one monoclonal anti-PDI directed against an epitope of PDI epitopes selected from SEQ ID No. 1, SEQ ID No 2 with an aromatic amino acid next to the three dimensional structure of PDI and SEQ ID No. 3.