GENETIC INSTABILITY BECAUSE OF BIORHYTHM DISTURBANCE

It is shown, that disturbance of proliferative activity rhythm leads to ineffective-ness of transferring damaged-DNA cells from proliferative pool to terminal dif-ferentiation. Thus, elimination of mutant cells is being violated, resulting accumulation of them in tissues. This might be the major cause of genetic instability increase, cancer diseases development and a number of other desynchronozis associated pathologic conditions.