NEUROPATHOLOGIC ASSESSMENT AND CLINICAL CORRELATES OF CHOROID PLEXUS HEMORRHAGE (CPH) IN A NEONATAL AUTOPSY POPULATION

To determine the incidence of neuropathologically-proven CPH and its correlation to birthweight (BW), gestational age (GA) and intrauterine growth, we reviewed the clinical courses and cranial postmortems of 81 consecutive neonates ≥500g BW who died between 6/1/80-5/31/82. Study cases represented 63% of all NICU deaths with specific exclusions for CNS malformations, severe brain autolysis and lack of parental permission for cranial postmortem. All post-mortem specimens were reviewed by a neuropathologist to determine intracranial hemorrhage (ICH) sites and extension.