The Effect of Anakinra on Paclitaxel-Induced Peripheral Neuropathic Pain in Rats
2017
Objective
Paclitaxel is used in the treatment of cancer, and it may cause interleukin-1 beta (IL-1β)-related peripheral neuropathic pain. While our primary aim was to investigate the analgesic efficacy of an IL-1β antagonist, a secondary outcome was to assess whether a correlation exists between analgesic effects and antioxidant activity.
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