Simple and efficient synthetic routes to s-triazinyl dithiocarbamate derivatives: 2,4-Diary lamino-6- (N -( 4' -ethox ypheny I )di thiocarbamoy I) -s-triazines and 2,4-bis­ (N-( 4' -ethoxyphenyl)dithiocarbamoy I) -6-ary lamino-s-triazines

Compounds 2,4-diarylamino-6-[N-(4'-ethoxyphenyl)dithiocarbamoyl]-s-triazines 4a-f and 2,4-his-[N-(4'-ethoxy-phenyl)dithiocarbamoyl]-6-arylamino-s-triazines 7a-f have been synthesized by two different methods. In the firstmethod (A) of preparation, 2,4,6-trichloro-s-triazine 1 is condensed with N-(4-ethoxyphenyl)ammoniumdithiocarbamate to afford 3 or 6 followed by the reaction with arylamines to afford 4a-f or 7a-f. In the second method (B) of preparation, 1 is condensed with arylamines to yield 2a-f or 5a-f followed by the action of N-(4-ethoxyphenyl)ammoniumdithiocarbamates to yield 4a-f or 7a-f. The constitutions of newly synthesised compounds 4a-f and 7a-f have been established on the basis of elemental analyses, IR and PMR spectral data. Antimicrobial activity of compounds 4a-f and 7a-f are performed by using cup-plate method against gram-positive bacteria, gram-negative bacteria and antifungal fungi. All the synthesised compounds have shown significant antimicrobial activity.