Applications of N′-alkylated derivatives of TsDPEN in the asymmetric transfer hydrogenation of CO and CN bonds

Abstract Arene/Ru(II) complexes of ( R , R )- N -alkyl-TsDPEN ligands are effective in the asymmetric transfer hydrogenation of ketones and imines in formic acid/triethylamine solution. The complex derived from the N ′-Bn derivative of TsDPEN reduces monocyclic imines in up to 60% ee, whilst the N ′-Me derivative of TsDPEN forms a more active catalyst than the non-alkylated analogue and reduces ketones in up to 97% ee.