Abstract 18404: Decreased and Increased Serum Calcium Levels Are Independent Predictors of In-hospital Mortality in Patients With Acute Myocardial Infarction

Introduction: serum calcium concentration, mg/dL (sCa) was reported to be associated with cardiovascular risk factors, incidence of coronary artery disease and of AMI. Furthermore, low, but not high, sCa were recently reported to predict increased mortality in patients with AMI. Hypothesis: we assessed the hypothesis that increased and decreased sCa independently predict in-hospital mortality in patients with AMI. Methods: a retrospective analysis of patients admitted in a tertiary medical center with AMI throughout 2002-2012 was performed. Exclusion criteria: chronic dialysis or missing sCa levels. Following correction of all sCa to corresponding albumin levels, mean sCa was calculated for each patient. Thereafter, the mean corrected sCa were categorized into 7 equally-sized groups as following: <8.9, 8.9-9.12, 9.12-9.3, 9.3-9.44, 9.44-9.62, 9.62-9.86, ≥9.86 mg/dL. The primary outcome was all-cause in-hospital mortality. Results: out of 12,121 AMI patients, 11,446 were included, mean age 67.1 ±14 years, ...