Chapter 10:Transcription Termination Factor Rho: A Ring-Shaped RNA Helicase from Bacteria

Many NTP-dependent protein machines form oligomeric structures resembling doughnouts.1–3 Such ring-shaped machines include DNA translocases such as viral DNA packaging motors4 or chromosomal segregation enzymes5 as well as numerous DNA helicases involved in recombination and replication.1,6–8 In con...