NMD and microRNA expression profiling of the HPCX1 locus reveal MAGEC1 as a candidate prostate cancer predisposition gene

Henna Mattila,Martin Schindler,Jarkko Isotalo,Tarja Ikonen,Mauno Vihinen,Hannu Oja,Teuvo L.J. Tammela,Tiina Wahlfors,Johanna Schleutker

NMD and microRNA expression profiling of the HPCX1 locus reveal MAGEC1 as a candidate prostate cancer predisposition gene

2011

Henna Mattila
Martin Schindler
Jarkko Isotalo
Tarja Ikonen
Mauno Vihinen
Hannu Oja
Teuvo L.J. Tammela
Tiina Wahlfors
Johanna Schleutker

Several predisposition loci for hereditary prostate cancer (HPC) have been suggested, including HPCX1 at Xq27-q28, but due to the complex structure of the region, the susceptibility gene has not yet been identified.

Keywords:

Cancer research
Pathology
Prostate cancer
microRNA
Gene expression profiling
Locus (genetics)
Mutation
Gene
Genotype
Microarray analysis techniques
Biology
Genetics
intensive care

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