GW26-e4479 Nrf2 Is Crucially Required for Sulforaphane to Prevent High Fat Diet/Low Dose STZ Induced Diabetic Cardiomyopathy

The present study aimed to define whether sulforaphane (SFN) protects from type 2 diabetic cardiomyopathy (DCM) entirely through Nrf2. 8 weeks of Nrf2-knockout (KO) and wild-types (WT, C57BL/6J) mice were used to induce a type 2 diabetes (T2DM), by feeding high-fat diet (HFD) for 3 months to induce