Melleumin A, a novel peptide lactone isolated from the cultured myxomycete Physarum melleum

Abstract Melleumin A ( 1 ), a novel peptide lactone, has been isolated from the laboratory-cultured plasmodium of myxomycete Physarum melleum , and its structure was elucidated by spectral data. Melleumin A ( 1 ) consisted of four residues ( p -methoxybenzoic acid, l -threonine, glycine, and an unusual amino acid, a tyrosine-attached acetic acid).