Crystal-structures of Lorazepam Acetone Solvate[i] and Normal-butyl Alcohol Solvate[ii]

The crystal structures of lorazepam acetone [I] and lorazepam n-butyl alcohol [II] solvates are determined. [I] is triclinic, P-1 with a = 12.602(2), b = 8.626(1), c = 8.610(1) angstrom; alpha = 72,27(1), beta = 74.66(1), gamma = 78.82(1)degrees; V = 853.2(2) angstrom 3, D(x) = 1.44 g.cm-3, lambda (Cu K-alpha) = 1.54178 angstrom, F(000) = 392, R = 0.068 for 2990 observed reflections. [II] is monoclinic, C2/c, with a = 26.466(13), b = 10.947(3), c = 13.906(7) angstrom; beta = 103.13 (4)degrees; V = 3924 (3) angstrom 3, D(x) = 1.388 g.cm-3, lambda (Mo K-alpha) = 0.71069 angstrom, F(000) = 1648, R = 0.09 for 1887 observed reflections. These crystal structures are compared with analogous molecules.