Clinical analysis of 5 invasive fungal rhinosinusitis cases

Objective:To discuss the clinical characteristics, treatment and prognosis of invasive fungal rhinosinusitis (IFRS). Method:Among the five patients who were diagnosed as IFRS, 4 patients had history of diabetes mellitus, and 1 case had a history of leukemia and chemotherapy. All the patients were treated through operation and antifungal therapy. Result:The patients were followed 1 year to 3 years after the operation. And 3 patients were clinical cured, 1 was died because of relapse, and 1 was died because of exacerbation. Conclusion:The diagnosis and treatment of IFRS need to be considered through many aspects. Antifungal therapy and medical treatment based on surgery might improve the recovery rate.