Budget IVF Using Clomiphene, hMG, and Antagonists
2015
Over the last three decades, several different ovarian stimulation protocols for in vitro fertilization (IVF) have been proposed and tried. The most commonly used gonadotropin-releasing hormone (GnRH) agonist long protocol has several advantages like good predictability, easier cycle management, lower cancellation rates, a higher number of oocytes and embryos, and better pregnancy rates. However, its use has been plagued with unpredictable multiple births and morbidity of ovarian hyperstimulation syndrome (OHSS). In addition to being physically and emotional stressful, it is costly and is unaffordable to a significant number of patients.
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