Atrial natriuretic factor in essential hypertension.

Abstract We measured circulating levels of immunoreactive atrial natriuretic factor (ANF) in 10 patients with untreated, uncomplicated mild to moderate essential hypertension and in 15 normotensive controls. ANF concentrations were significantly higher in the hypertensive group than in the control group (38.4 ± 6.9 pg/ml versus 18.3 ± 1.8 pg/ml, p