Chemical Constituents of the Aerial Parts of Euphorbia nematocypha

Chemical constituents of the dried aerial parts of euphorbia nematocypha were investigated. a new oleanane triterpenoid, trans, trans-2',4'-hexadienedioicacid-1'-beta-amyrin ester (1), together with, beta-amyrin (2), beta-amyrin acetate (3), betulinic acid (4), ellagic acid (5), oleanolic acid (6), beta-sitosterol (7), kaempferol (8), quercetin (9), lupeol (10) and pseudo-taraxasterol (11) were isolated from the methylene chloride extract. their structures were elucidated on the basis of extensive spectroscopic (1d- & 2d-nmr) and esi-ms analysis and comparison with data reported in the literature. the new isolated triterpenoid showed moderate cytotoxic activities against hela and mcf-7cell lines.