TAURINE LEVELS IN PLASMA AND PLATELETS IN INSULIN-DEPENDENT AND NON-INSULIN-DEPENDENT DIABETES MELLITUS: CORRELATION WITH PLATELET AGGREGATION

In human volunteers it has been shown that taurine supplementation decreases collagen-induced thromboxane release and platelet aggregation (6). In addition, we found that, while in vitro taurine did not modify platelet aggregation per se, it potentiated the effect of anti-aggregating agents such as aspirin, papaverine, or sodium nitroprusside (13). These observations seem to indicate a possible role for taurine in the modulation of platelet function.