PI3Kα in cardioprotection: Cytoskeleton, late Na+ current, and mechanism of arrhythmias

ABSTRACTPI 3-kinase α (PI3Kα) is a lipid kinase that converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-triphosphate (PIP3). PI3Kα regulates a variety of cellular p...