Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes

D. H. Jensen,Kasper Aaboe,Jan Erik Henriksen,Anders Vølund,Jens J. Holst,Sten Madsbad,Troels Magelund Krarup

Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes

2012

D. H. Jensen
Kasper Aaboe
Jan Erik Henriksen
Anders Vølund
Jens J. Holst
Sten Madsbad
Troels Magelund Krarup

Aims/hypothesis The aim of this study was to evaluate the separate impact of insulin resistance and impaired glucose tolerance (IGT) on the incretin effect.

Keywords:

Insulin resistance
Incretin
Glucagon-like peptide-1
Impaired glucose tolerance
Diabetes mellitus
First-degree relatives
Type 2 diabetes
Glucose tolerance test
Endocrinology
Biology
Internal medicine

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