The incidence of endophtalmitis after the application of intravitreal injections in FNKV with regard to various prophylactic antibiotic regimens

AIM: Comparing the incidence of endophtalmitis at the Ophthalmologic clinic of FNKV after the application of intravitreal injections with regard to various prophylactic antibiotic regimens.Methodics: Comparing the number of endophtalmitis cases during the period of 2005-2011, when the intravitreal applications were secured by full antibiotic prophylaxis (Floxal)/Oftaquix gtt. 5xd 3 days before the application and 3 days after the application with the years of 2012-2013, when Vigamox gtt. was used during the preparation of the eye before surgery to prevent inflammatory changes. RESULTS: In the years of 2005-2013, 5005 injections were applied. In total we recorded three cases of endophthalmitis. In all cases, a pars plana vitrectomy with sample collection for culture and microbiological analysis was performed. During the years of 2005-2011, 2 651 injections were applied with two cases of endophtalmitis (0,075%, 1:1 325, both cases culture-negative). During the years of 2012-2013, 2 355 injections were applied with one case of endophtalmitis (0,042 %, 1:2 355, culture-positive). CONCLUSION: According to our experience, limited prophylactic antibiotic regimen does not increase the incidence of endophtalmitis in comparison with full prophylactic antibiotic regimen.