Tendinosis-like histologic and molecular changes of the Achilles tendon to repetitive stress: a pilot study in rats.

Background Tendinopathy (pain and tendon degeneration) is associated with repetitive use and mechanical overload. However, the etiology of tendinopathy remains unclear. Clarification of histologic and molecular changes of tendon to repetitive stress could provide better understanding of Achilles tendon disorders related to repetitive stress.