Copenhagen Head Injury Ciclosporin (CHIC) study: A phase IIa safety, pharmacokinetics and biomarker study of ciclosporin in severe head injury patients

Jesper Kelsen,Michael Karlsson,Magnus J. Hansson,Zhihui Yang,Walter Fischer,Matilda Hugerth,Carl-Henrik Nordström,Ramona Åstrand,Marcus F. Keep,Todd J. Kilbaugh,Kevin K. W. Wang,Kirsten Møller,Marianne Juhler,Eskil Elmér

Copenhagen Head Injury Ciclosporin (CHIC) study: A phase IIa safety, pharmacokinetics and biomarker study of ciclosporin in severe head injury patients

2019

Jesper Kelsen
Michael Karlsson
Magnus J. Hansson
Zhihui Yang
Walter Fischer
Matilda Hugerth
Carl-Henrik Nordström
Ramona Åstrand
Marcus F. Keep
Todd J. Kilbaugh
Kevin K. W. Wang
Kirsten Møller
Marianne Juhler
Eskil Elmér

Abstract Traumatic brain injury (TBI) contributes to almost one third of all trauma-related deaths, and those that survive often suffer from long-term physical and cognitive deficits. Ciclosporin (...

Keywords:

Biomarker (medicine)
Anesthesia
Head injury
Ciclosporin
Medicine
Pharmacokinetics
MEDLINE
Traumatic brain injury
Neurology
Pharmaceutical sciences

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